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Browsing Posts tagged ReNeuron

DIABETES

On the third of March 2010, UK based leading stem cell Therapy Company ReNeuron announced positive pre-clinical data for the treatment of Peripheral Arterial Disease (PAD) in Diabetic Patients using its indigenously developed Stem cell line ReN009. PAD occurs when there is a build-up of plaque in the arteries. This plaque generally is made up of fats and cholesterol, calcium and fibrous components of the body. Periodic build-up of such fats in the arteries can cause them to harden and narrow the lumen (Hollow space) of the artery. This narrowing prevents proper blood flow within the body. Known as Atherosclerosis, this generally affects blood flow to the legs but can also affect flow to kidneys hands and other parts of the body. PAD is a chronic and debilitating disease that progressively restricts blood flow in the limbs, causing cramping, chronic pain and in extreme cases, amputation.  PAD is commonly associated with other conditions, including diabetes, obesity and stroke.  At least 1 in 20 people over the age of 55 have some degree of PAD and it becomes more common with increasing age. For more on this disease please click here

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We have all heard of stem cells. These are the magical ‘starter cells’ that have the capacity to grow into any type of differentiated cell of the adult body. If given optimal growth conditions and with some amount of external hormonal supplementation, theoretically one can induce these multi-potent cells to grow into say liver cells, or brain cells for that matter.

The discovery of this unique potential of these cells led to the probability of using them for therapy. What If these stem cells could be harvested and grown externally in a medium and then transplanted into patients having a chronic dysfunction of cells or organs systems? This would indeed be a much-needed breakthrough in the field of therapeutics. Thus was born the idea of Stem Cell Therapy. The process of injecting stem cells into a person or organism to repair specific tissues or to grow organs is known as Stem Cell Therapy.

Over the years Stem cell research has progressed significantly and the latest news in this field stands testimony to the hard work and relentless research of scientists working in this field. The ReNeuron Group on the second of February, 2010, announced that the UK Gene Therapy Advisory Committee (GTAC) has given a “full and final Favorable Opinion to ReNeuron’s proposed first-in-man clinical trial with its ReN001 stem cell therapy for stroke.”  The GTAC is the national research ethics committee for gene therapy and stem cell therapy clinical trials in the UK. The ReNeuron Company is a Guildford (UK) based stem cell research company. This approval represents the final stage in a long process the company has been going to through to gain approval to test its expanded neural stem cell line on patients suffering from Ischemic stroke. In the official website, the company makes the following declaration:  ‘We have received regulatory and conditional ethical approvals to commence a ground-breaking Phase I clinical trial in the UK with our lead ReN001 stem cell therapy for disabled stroke patients. We are developing stem cell therapies for a number of other conditions, including peripheral arterial disease and diseases of the retina.’ continue reading…